BDBM50454158 CHEMBL4207495

SMILES COc1ccc(cc1)C(CC(=O)Nc1ccc(cc1)C(C)(C)C)N(C)C(=O)c1ccc(=O)[nH]c1

InChI Key InChIKey=CJGMUGCAQBRQJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454158   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454158(CHEMBL4207495)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of BODIPY-cholesterol from human His-tagged RORgammat after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50454158(CHEMBL4207495)
Affinity DataIC50: >3.00E+4nMAssay Description:Inverse agonist activity at RORgammat in human Jurkat cells assessed as inhibition of transcriptional activity after overnight incubation by human IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed