BDBM50455873 CHEMBL4216801
SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(C[C@@H]3CNC(=O)CO3)c(cc12)C#N
InChI Key InChIKey=JTUOGOXWKQAKOR-NRFANRHFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50455873
Affinity DataIC50: 3.60nMAssay Description:Displacement of fluorescein-labeled MLL4-43 from full length human menin expressed in Escherichia coli BL21 (DE3) cells after 3 hrs by fluorescence p...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human Menin expressed in Escherichia coli Rosetta2 (DE3) cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 9nMAssay Description:Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometryMore data for this Ligand-Target Pair