BDBM50456109 CHEMBL4212119

SMILES CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(SCc2ccc(F)cc2)n1

InChI Key InChIKey=LDKFMROXBKEDTL-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456109   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataKd:  1nMAssay Description:Binding affinity to DNA-tagged human partial length TrkA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataKd:  25nMAssay Description:Binding affinity to DNA-tagged human partial length AURKA expressed in mammalian expression system by qPCR methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Heidelberg University

Curated by ChEMBL
LigandPNGBDBM50456109(CHEMBL4212119)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at C-terminal PK-fused human full length TrkA assessed as inhibition of betaNGF-induced protein binding to Shc1-EA by beta-galact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed