BDBM50456585 CHEMBL4218664
SMILES COc1ccc(cc1)-c1cn(C[C@H]2NC[C@@H](O)[C@H]2O)nn1
InChI Key InChIKey=ULCQBQQZAQOXJM-MCIONIFRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50456585
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataKi: 1.90E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins f...More data for this Ligand-Target Pair
Affinity DataKi: 7.50E+4nMAssay Description:Competitive inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.38E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured aft...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human recombinant lysosomal GCase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followed by s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of human recombinant lysosomal alpha-GalA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Universidad De Sevilla
Curated by ChEMBL
Universidad De Sevilla
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human lysosomal beta-glucocerebrosidase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 45 mins followe...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of coffee beans alpha-galactosidase using p-nitrophenyl glycopyranoside preincubated for 5 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.85E+5nMAssay Description:Inhibition of human lysosomal alpha-galactosidase A using 4-methylumbelliferyl-alpha-D-galactopyranoside as substrate preincubated for 45 mins follow...More data for this Ligand-Target Pair