BDBM50457452 SB-590885::SB590885
SMILES CN(C)CCOc1ccc(cc1)-c1nc(c([nH]1)-c1ccc2\C(CCc2c1)=N\O)-c1ccncc1
InChI Key InChIKey=MLSAQOINCGAULQ-QFMPWRQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50457452
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 0.160nMAssay Description:Inhibition of full length human 6His-tagged BRAF V600E mutant expressed in baculovirus infected insect cells co-expressing human CDC37 (1 to 378 resi...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Albert Einstein College Of Medicine
Curated by ChEMBL
Albert Einstein College Of Medicine
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of BRAF V600E mutant in human A375 cells assessed as reduction in ERK phosphorylation by immunoblot analysisMore data for this Ligand-Target Pair