BDBM50457986 CHEMBL4209777
SMILES O=C(Nc1ccccc1-c1nnn(n1)-c1ccccc1)C12CC3CC(CC(C3)C1)C2
InChI Key InChIKey=CNMKKLGKUOVNHL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50457986
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T Bonn
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T Bonn
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of ABCB1 in human A2780adr cells assessed as reduction in calcein AM levels preincubated for 30 mins followed by calcein AM addition measu...More data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Rheinische Friedrich-Wilhelms-Universit£T Bonn
Curated by ChEMBL
Rheinische Friedrich-Wilhelms-Universit£T Bonn
Curated by ChEMBL
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of C-terminal GFP-fused human ABCG2 expressed in MDCK2 cells preincubated for 30 mins followed by Hoechst 33342 addition and measured ever...More data for this Ligand-Target Pair