BDBM50458606 CHEMBL4205511

SMILES CC(Cc1cccc(n1)-n1c(cc2ccc(OC(F)(F)F)cc12)C(N)=O)C(O)=O

InChI Key InChIKey=ASLSDJNSUCRUHC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50458606   

TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  65nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  510nMAssay Description:Inhibition of sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  65nMAssay Description:Inhibition of sPLA2-10 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  92nMAssay Description:Inhibition of sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of sPLA2-5 (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGroup 10 secretory phospholipase A2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant human sPLA2-10 using human HDL as substrate pretreated for 20 mins followed by substrate addition and measured after 60 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50458606(CHEMBL4205511)
Affinity DataIC50:  92nMAssay Description:Inhibition of sPLA2-2A (unknown origin) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate pretreated for 20 mins followed by substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed