BDBM50458927 CHEMBL4214637

SMILES Clc1cccc(COc2cccc3onc(Nc4cccnc4)c23)c1

InChI Key InChIKey=NDSZUDJYEHKGLF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458927   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50458927(CHEMBL4214637)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50458927(CHEMBL4214637)
Affinity DataIC50:  100nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed