BDBM504590 US11040966, Example 4.1::[(2S,3S)-3-Methyl-2-(4-methyl-1H-benzoimidazol-2-yl)-pyrrolidin-1-yl]-(5-methyl-2-[1,2,3]triazol-2-yl-phenyl)-methanone

SMILES C[C@H]1CCN([C@@H]1c1nc2c(C)cccc2[nH]1)C(=O)c1cc(C)ccc1-n1nccn1

InChI Key InChIKey=JALZGXKNABSZPI-KKSFZXQISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504590   

TargetOrexin receptor type 2(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504590(US11040966, Example 4.1 | [(2S,3S)-3-Methyl-2-(4-m...)
Affinity DataIC50:  778nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM504590(US11040966, Example 4.1 | [(2S,3S)-3-Methyl-2-(4-m...)
Affinity DataIC50:  29nMAssay Description:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 receptor, respectively, are grown in culture medium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent