BDBM50459055 CHEMBL4207715

SMILES NC(=N)NC(=O)c1nc(-c2cc3c(F)cccc3o2)c(nc1N)N1CCCCCC1

InChI Key InChIKey=ITMHCPYYAUUUAC-UHFFFAOYSA-N

Data  1 KI  8 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50459055   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataKi:  88nMAssay Description:Inhibition of human kidney uPA using Z-Gly-Gly-Arg-AMC as substrate measured over 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTissue-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of tPA (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetVitamin K-dependent protein C(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of activated protein C (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of factor 10a (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of thrombin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of plasmin (unknown origin) using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50:  430nMAssay Description:Inhibition of human kidney uPA using chromogenic H-D-Ile-L-Pro-L-Arg-p-nitoraniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPlasma kallikrein(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of human plasma kallikrein using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50459055(CHEMBL4207715)
Affinity DataIC50:  2.33E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using chromogenic L-pyroGlu-L-Pro-L-Arg-p-nitroaniline as substrate by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed