BDBM50459230 CHEMBL4215472

SMILES OC(=O)c1noc(c1-c1cccc(c1)-c1cc(Cl)c(O)c(c1)[N+]([O-])=O)-c1ccccc1

InChI Key InChIKey=SPIZPABAPBQRSM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50459230   

TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human VHR using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB H94A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  3.13E+5nMAssay Description:Inhibition of human PTP1B using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  780nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB R136A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  400nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459230(CHEMBL4215472)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB E129A mutant expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed