BDBM50459752 CHEMBL4206167

SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(=O)N[C@@H](Cc1ccc(OCCN)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@](C)(CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(N)=O)NC(C)=O

InChI Key InChIKey=YCYOWXTYVQGGHS-XKGNXMRFSA-N

Data  2 IC50  1 Kd  1 Koff

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50459752   

TargetInterleukin-23 receptor(Homo sapiens)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50:  2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataKd:  1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataIC50:  5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterleukin-23 receptor(Homo sapiens)
Centro De Investigaci£N Lilly

Curated by ChEMBL
LigandPNGBDBM50459752(CHEMBL4206167)
Affinity DataKon:  0.0274M-1s-1Assay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as dissociation rate constant me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed