BDBM50459752 CHEMBL4206167
SMILES C[C@@H](O)[C@@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCSC[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(=O)N[C@@H](Cc1ccc(OCCN)cc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@](C)(CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(N)=O)NC(C)=O
InChI Key InChIKey=YCYOWXTYVQGGHS-XKGNXMRFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50459752
Affinity DataIC50: 2.70nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Affinity DataKd: 1.81nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells measured over 90 secs by surface plasmon ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.10nMAssay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as disruption of biotinylated IL...More data for this Ligand-Target Pair
Affinity DataKon: 0.0274M-1s-1Assay Description:Binding affinity to recombinant human flag/His-tagged IL-23R (1 to 353 residues) expressed in HEK293F cells assessed as dissociation rate constant me...More data for this Ligand-Target Pair