BDBM50460352 CHEMBL4227145

SMILES Cc1cccc(C)c1C(=O)NC(c1ccccc1)C12CCC(CC1)N2

InChI Key InChIKey=LMVLUIGCBTZPJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460352   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460352(CHEMBL4227145)
Affinity DataIC50:  58nMAssay Description:Inhibition of recombinant human GlyT1 expressed in CHO cells assessed as reduction in [3H]glycine uptake pretreated for 15 mins followed by [3H]glyci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed