BDBM50460359 CHEMBL4228578

SMILES COc1ccc(cc1)C(NC(=O)c1cccc(c1Cl)C(F)(F)F)C12CCC(CC1)CN2C

InChI Key InChIKey=SIMBCGZPFCTLFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460359   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460359(CHEMBL4228578)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of recombinant human GlyT1 expressed in CHO cells assessed as reduction in [3H]glycine uptake pretreated for 15 mins followed by [3H]glyci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed