BDBM50460370 CHEMBL4228770

SMILES CN1CC2CCC1(CC2)[C@@H](NC(=O)c1cccc(c1Cl)C(F)(F)F)c1ccccc1

InChI Key InChIKey=DEXIHFHWGDUZEE-BGWLNWIQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50460370   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460370(CHEMBL4228770)
Affinity DataIC50:  41nMAssay Description:Inhibition of recombinant human GlyT1 expressed in CHO cells assessed as reduction in [3H]glycine uptake pretreated for 15 mins followed by [3H]glyci...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed