BDBM50460791 CHEMBL4227284

SMILES Cc1cn2c(cnc2c(Nc2cc(ns2)C(N2CCCCC2)c2ccccn2)n1)-c1cn[nH]c1

InChI Key InChIKey=JGQWCDPUDLKBMX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50460791   

TargetAurora kinase B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50460791(CHEMBL4227284)
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50460791(CHEMBL4227284)
Affinity DataIC50: <4nMAssay Description:Inhibition of Aurora A (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50460791(CHEMBL4227284)
Affinity DataIC50: <13nMAssay Description:Inhibition of Aurora B (unknown origin) using Tamra-PKAtide as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed