BDBM50461485 CHEMBL4228072

SMILES Nc1nc2cc(cc(CCC(O)=O)c2c(=O)n1CC1CCCO1)-c1ccc(CCCc2ccccc2)cc1

InChI Key InChIKey=MYJBZTCPVQPNGD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50461485   

TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461485(CHEMBL4228072)
Affinity DataIC50:  80nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-2 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin I(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461485(CHEMBL4228072)
Affinity DataIC50:  740nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin-1 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPlasmepsin II(Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461485(CHEMBL4228072)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of Plasmodium falciparum 3D7 plasmepsin IIMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlasmepsin IV [1-448](Plasmodium falciparum)
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461485(CHEMBL4228072)
Affinity DataIC50:  30nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 4 using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Latvian Institute Of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50461485(CHEMBL4228072)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human cathepsin D using DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed