BDBM50461646 CHEBI:582124::Myriocin

SMILES CCCCCCC(=O)CCCCCC\C=C\C[C@@H](O)[C@H](O)[C@@](N)(CO)C(O)=O

InChI Key InChIKey=ZZIKIHCNFWXKDY-GNTQXERDSA-N

Data  1 IC50  1 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461646   

TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)
Affinity DataEC50:  50nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
TargetSerine palmitoyltransferase 2(Homo sapiens (Human))
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)
Affinity DataIC50:  0.130nMAssay Description:Inhibition of human SPT2 transfected in Freestyle293 cells using L-serine and palmitoyl-CoA as substrate preincubated for 60 mins followed by substra...More data for this Ligand-Target Pair