BDBM50462090 CHEMBL4242095

SMILES CSc1sc(cc1S(=O)(=NS(=O)(=O)c1cccc(NC(N)=O)c1)c1cccc(c1)-c1c(C)cc(NC(N)=N)cc1N)C(N)=N

InChI Key InChIKey=VVGBUDHDUBJJKT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462090   

TargetComplement C1s subcomponent(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462090(CHEMBL4242095)
Affinity DataKi:  11nMAssay Description:Inhibition of human plasma C1s using Cbz-Gly-Arg-S-Bzl as substrate preincubated with substrate for 15 mins followed by enzyme addition and measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMannan-binding lectin serine protease 2(Homo sapiens)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462090(CHEMBL4242095)
Affinity DataKi:  440nMAssay Description:Inhibition of human His-tagged MASP-2 (Cys300 to Phe686 residues) expressed in baculovirus infected insect cells using Z-Gly-Arg-S-Bzl as substrate p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed