BDBM50462775 CHEMBL4248273::US10508105, Compound 20

SMILES Cn1nc(OC2CCOCC2)c2ccc(Nc3n[nH]c4cccnc34)cc12

InChI Key InChIKey=HZAPEUKZUCPGNJ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462775   

TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50462775(CHEMBL4248273 | US10508105, Compound 20)
Affinity DataEC50:  45.4nMAssay Description:The disclosed compounds and compositions can be evaluated for their ability to act as a potentiatior of metabotropic glutamate receptor activity, in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50462775(CHEMBL4248273 | US10508105, Compound 20)
Affinity DataEC50:  45nMAssay Description:Positive allosteric modulation of human mGluR4 expressed in CHO cells co-expressing Gqi5 assessed as increase in glutamate-induced calcium flux prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed