BDBM50463507 CHEMBL4247751
SMILES Cc1nc2ccc(c(C)c2c(=O)[nH]1)-c1ccnc2ccccc12
InChI Key InChIKey=CNEUJSQUCXSRDD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50463507
Affinity DataKd: 640nMAssay Description:Binding affinity to human ALK2 by KdELECT assayMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 330nMAssay Description:Binding affinity to partial length human RAF1 (I330 to T640 residues) expressed in bacterial expression system by KdELECT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 41nMAssay Description:Binding affinity to human ALK1 by KdELECT assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 65nMAssay Description:Binding affinity to partial length human BRAF (S429 to E741 residues) expressed in mammalian expression system by KdELECT assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 2.70E+3nMAssay Description:Binding affinity to human ALK3 by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataKd: 690nMAssay Description:Binding affinity to human ALK4 by KdELECT assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to human ALK5 by KdELECT assayMore data for this Ligand-Target Pair
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Institute Of Cancer Research
Curated by ChEMBL
Institute Of Cancer Research
Curated by ChEMBL
Affinity DataKd: 39nMAssay Description:Binding affinity to human ALK6 by KdELECT assayMore data for this Ligand-Target Pair