BDBM50463982 CHEMBL4239987
SMILES CCCN(CCc1ccc(NC(=O)CCc2cn(CCCCCCNC(=O)COc3cncc(c3)C#Cc3csc(C)n3)nn2)cc1)C1CCc2c(O)cccc2C1
InChI Key InChIKey=FFSGPPYSYVXBKP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50463982
Affinity DataKi: 142nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes co-expressing mGluR5a (unknown origin...More data for this Ligand-Target Pair
Affinity DataKi: 295nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes after 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor/Metabotropic glutamate receptor 5(Human)
Ghent University
Curated by ChEMBL
Ghent University
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Agonist activity at human dopamine D2 receptor /mGluR5a (unknown origin) expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP a...More data for this Ligand-Target Pair
Affinity DataEC50: 7.60nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in HEK293T cells assessed as reduction in forskolin-induced cAMP accumulation preincubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair