BDBM50464787 CHEMBL4293027

SMILES COc1cc2CCN(CCCCN3C\C(=N/NC(=S)N(C)C)c4ccccc34)C(=O)c2cc1OC

InChI Key InChIKey=BYZLKBXRKFWFHW-SZXQPVLSSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464787   

TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50464787(CHEMBL4293027)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes in presence of (+)-pentazocine by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50464787(CHEMBL4293027)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK-MDR1 cells assessed as calcein cell accumulation after 30 mins by spectrofluorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed