BDBM50465362 CHEMBL4286544

SMILES CNc1nc(Nc2ccc(c(F)c2)-n2cnc(C)n2)nc2N(CCC(C)(C)c12)c1ccc(F)cc1

InChI Key InChIKey=LLCQLIVLLRLJSJ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465362   

TargetPresenilin-1(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50465362(CHEMBL4286544)
Affinity DataEC50:  8nMAssay Description:Inhibition of gamma-secretase in human H4 cells harboring APP695 K595N/M596L swedish mutant after 24 hrs by AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed