BDBM50466206 CHEMBL4281335
SMILES C[C@H]1CN(C[C@@H](C)O1)c1ccc(Nc2nc(ccc2C(N)=O)N2CC[C@@H](C2)NC(=O)C=C)cc1
InChI Key InChIKey=YQBSMRRMOZCNRZ-SCTDSRPQSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50466206
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of full length human BTK (8 to 80 residues) using FITC-AHA-EEPLYWSFPAKKK-NH2 as substrate after 90 mins by off-chip mobility shift assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of BTK in human PBMCMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of BTK in human WBCMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of BTK in human whole bloodMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged BTK (2 to 659 residues) expressed in baculovirus expression system using FITC-AHA-E...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of BTK in goat anti-human IgM F(ab')2-stimulated human PBMC assessed as suppression of BCR-induced CD69 expression on B cells pretreated f...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Emd Serono Research & Development Institute
Curated by ChEMBL
Emd Serono Research & Development Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair