BDBM50466381 CHEMBL4281750

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)C(C)(C)C(=O)Nc2cccc(F)c2)cc1

InChI Key InChIKey=IKKTYHVOFCDTIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466381   

TargetNuclear receptor ROR-gamma(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466381(CHEMBL4281750)
Affinity DataIC50:  260nMAssay Description:Transrepression of recombinant mouse GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466381(CHEMBL4281750)
Affinity DataIC50:  290nMAssay Description:Transrepression of RORgammat in anti-CD3/CD28 stimulated C57BL/6 mouse CD4-positive T cells assessed as suppression of T cell differentiation to Th17...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50466381(CHEMBL4281750)
Affinity DataIC50:  9.80nMAssay Description:Transrepression of recombinant human GAL4-DBD fused RORgammat LBD expressed in HEK293 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed