BDBM50466478 CHEMBL4288744

SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1

InChI Key InChIKey=OONQMOVZTSXSFX-XODNFHPESA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50466478   

TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataKi:  1.70E+3nMAssay Description:Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50:  9.40E+3nMAssay Description:Inhibition of recombinant human Ptp1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant human LYP using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase YopH(Yersinia enterocolitica)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of recombinant Yersinia enterocolitica YopH using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Homo sapiens (Human))
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50466478(CHEMBL4288744)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of recombinant human PTP-PEST using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed