BDBM50467476 CHEMBL4280648
SMILES [H][C@@]12Cc3c([nH]c4ccccc34)[C@H](N1C(=O)N(CCCC)C2=O)c1ccc(CC)s1
InChI Key InChIKey=MHKSTLAWFJQTLC-GHTZIAJQSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50467476
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE11A4 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged PDE2A (2 to 941 residues) expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AM...More data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE3B (592 to end residues) expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-A...More data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE1A expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as subs...More data for this Ligand-Target Pair
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE6C expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as subs...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE5A1 expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-GMP as sub...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Shandong University
Curated by ChEMBL
Shandong University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PDE4A1A expressed in baculovirus infected sf9 cells using FAM-cyclic-3',5-AMP as su...More data for this Ligand-Target Pair