BDBM50468755 CHEMBL4283764

SMILES CC(=O)NC1=NN(C(C)=O)[C@@](C)(S1)c1ccccc1

InChI Key InChIKey=JEFVYQYZCAVNTP-ZDUSSCGKSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468755   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50:  580nMAssay Description:Inhibition of basal ATPase activity of N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataIC50:  493nMAssay Description:Inhibition of N-terminal His6-tagged microtubule-stimulated ATPase activity of human Eg5 motor domain (1 to 368 residues) expressed in Escherichia co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50468755(CHEMBL4283764)
Affinity DataKd:  220nMAssay Description:Binding affinity to N-terminal His6-tagged human Eg5 motor domain (1 to 368 residues) expressed in Escherichia coli BL21 (DE3) by isothermal titratio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed