BDBM50468940 CHEMBL4291904

SMILES Fc1ccccc1-c1cc2nc(-c3ccco3)c(nc2cc1Br)-c1ccco1

InChI Key InChIKey=QPFJYOBFDADWOP-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50468940   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Chongqing University

Curated by ChEMBL
LigandPNGBDBM50468940(CHEMBL4291904)
Affinity DataEC50:  1.57E+4nMAssay Description:Inhibition of PI3K-delta (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50468940(CHEMBL4291904)
Affinity DataEC50:  137nMAssay Description:Inhibition of recombinant full length PI3K p85alpha/p110alpha H1047R mutant (unknown origin) expressed in baculovirus infected sf9 cells using PIP2 a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Chongqing University

Curated by ChEMBL
LigandPNGBDBM50468940(CHEMBL4291904)
Affinity DataEC50:  9.89E+3nMAssay Description:Inhibition of PI3K-gamma (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Chongqing University

Curated by ChEMBL
LigandPNGBDBM50468940(CHEMBL4291904)
Affinity DataEC50:  3.34E+3nMAssay Description:Inhibition of PI3K-beta (unknown origin) after 40 mins by Kinase-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50468940(CHEMBL4291904)
Affinity DataEC50:  93nMAssay Description:Inhibition of recombinant full length PI3K p110alpha/p85alpha (unknown origin) expressed in baculovirus infected sf9 cells using PIP2 as substrate pr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed