BDBM50468983 CHEMBL4282506
SMILES O=C(CC#N)N\N=C1/C(=O)Nc2ccc(cc12)S(=O)(=O)N1CCOCC1
InChI Key InChIKey=WPPDHWSWHZDVQN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50468983
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition and...More data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human EGFR T790M mutant expressed in baculovirus infected Sf21 insect cells preincubated for 5 mins f...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR in human HepG2 cellsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1/2/3(Homo sapiens (Human))
Al-Azhar University
Curated by ChEMBL
Al-Azhar University
Curated by ChEMBL
Affinity DataIC50: 276nMAssay Description:Inhibition of GST-tagged recombinant human VEGFR (789-end) expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins followed by ATP...More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Al-Azhar University
Curated by ChEMBL
Al-Azhar University
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human GST-tagged HER2 (676-end) expressed in baculovirus infected Sf9 insect cells preincubated for 5 mins followed by ATP ...More data for this Ligand-Target Pair