BDBM50469276 CHEMBL4282782

SMILES O=C(CC#N)N\N=C\c1c[nH]c2ccccc12

InChI Key InChIKey=NDKPKOACXIITRW-OVCLIPMQSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50469276   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human COX-2 expressed in Baculovirus infected Sf21 cells using arachidonic acid as substrate preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Universidade Federal De Pernambuco (Ufpe)

Curated by ChEMBL
LigandPNGBDBM50469276(CHEMBL4282782)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed