BDBM50469323 CHEMBL4290675

SMILES Clc1cc(NC(=O)Nc2ccncc2)ccn1

InChI Key InChIKey=HFIPFTAKXMECCX-UHFFFAOYSA-N

Data  3 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50469323   

TargetTranscription activator BRG1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataKd:  280nMAssay Description:Binding affinity to His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant His10-tagged ZZ-HCV3C-BRM ATPase-SnAC (636 to 1331 residues) (unknown origin) expressed in insect sf9 cells preincubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataKd:  87nMAssay Description:Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in absence of ADP by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataKd:  450nMAssay Description:Binding affinity to N-terminal avi-tagged BRM ATPase-SnAC domain (unknown origin) in presence of ADP by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTranscription activator BRG1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataIC50:  770nMAssay Description:Inhibition of recombinant His6-tagged BRG1 ATPase-SnAC (658 to 1361 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProbable global transcription activator SNF2L2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50469323(CHEMBL4290675)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of full length BRM ATPase (1 to 1572 residues) (unknown origin) expressed in insect sf9 cells preincubated for 5 mins followed by pCMV-dR8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed