BDBM50472586 CHEMBL44841

SMILES OC1(CNCc2cccc(n2)-n2cccn2)CCN(CC1)C(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=KRLHLVWNOUDUET-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50472586   

Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472586(CHEMBL44841)
Affinity DataKi:  1.60nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472586(CHEMBL44841)
Affinity DataEC50:  40nMAssay Description:In vitro effective concentration required to inhibit forskolin-stimulated cAMP levels in HA7 cells expressing human 5-HT1A receptorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed