BDBM50473686 CHEMBL433314
SMILES CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](CO)C(=O)NO)C(C)(C)C
InChI Key InChIKey=MOODLLAARDEUNJ-GRYCIOLGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50473686
Target72 kDa type IV collagenase(Homo sapiens (Human))
Preclinical Research Novartis Pharma
Curated by ChEMBL
Preclinical Research Novartis Pharma
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibitory potency against Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Preclinical Research Novartis Pharma
Curated by ChEMBL
Preclinical Research Novartis Pharma
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibitory potency against Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
Affinity DataKi: 9.80nMAssay Description:Inhibitory potency against Matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Preclinical Research Novartis Pharma
Curated by ChEMBL
Preclinical Research Novartis Pharma
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibitory potency against Tumor necrosis factor alpha converting enzyme (TACE)More data for this Ligand-Target Pair
TargetTumor necrosis factor(Homo sapiens (Human))
Preclinical Research Novartis Pharma
Curated by ChEMBL
Preclinical Research Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibitory activity against tumor necrosis factor alpha (TNF-alpha) production in LPS-stimulated human PBMCsMore data for this Ligand-Target Pair