BDBM50473890 CHEMBL2111820

SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@@H](C)OCc1ccccc1)C2(C)C

InChI Key InChIKey=VCCBCXVFGHTDQN-QQYUOCJXSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50473890   

TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataKi:  391nMAssay Description:Displacement of diltiazem from L-type calcium channel binding siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataKi:  500nMAssay Description:Displacement of verapamil from L-type calcium channel binding siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of DHP from L-type calcium channel binding siteMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-TTX from sodium channel of rat cerebral cortex synaptosomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 1/2/3 subunit alpha(Rattus norvegicus)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50473890(CHEMBL2111820)
Affinity DataIC50:  922nMAssay Description:Inhibitory effect against veratridine-induced glutamate release from rat brain slicesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed