BDBM50474800 CHEMBL304070

SMILES C(C1CCN(Cc2nc3ccccc3[nH]2)CC1)c1ccccc1

InChI Key InChIKey=WHMKZOBPYPISHR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50474800   

TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474800(CHEMBL304070)
Affinity DataKi:  420nMAssay Description:Compound was evaluated for in vitro inhibition of [3H][(E)-N-(2-methoxybenzyl)cinnamamidine binding to human NR1a/NR2B receptors expressed in LtK-cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474800(CHEMBL304070)
Affinity DataIC50:  710nMAssay Description:In vitro inhibition of Glu/Gly stimulated [Ca2+] influx in LtK-cells expressing the hNR1a/NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50474800(CHEMBL304070)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro inhibitory activity against alpha-1 adrenergic receptor binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed