BDBM50478075 CHEMBL271880

SMILES CC1(C)CCNC(=O)[C@@H](C1)N(Cc1ccc(cc1)C(=O)NC1CC1)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=UJHRYCHNFLBUEJ-JOCHJYFZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478075   

TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478075(CHEMBL271880)
Affinity DataIC50:  15nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed