BDBM50478081 CHEMBL272129

SMILES Clc1ccc(cc1)S(=O)(=O)N(Cc1ccc2OCOc2c1)C1CCCNC1=O

InChI Key InChIKey=HAENBDUKPFQEAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50478081   

TargetPresenilin-1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50478081(CHEMBL272129)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human gamma secretase in HEK293 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed