BDBM50479682 2-(4-Nitrophenyl)Benzo[D]Thiazole::CHEMBL477841

SMILES [O-][N+](=O)c1ccc(cc1)-c1nc2ccccc2s1

InChI Key InChIKey=KEJBDGQLLLLBGE-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50479682   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
K.U.Leuven

Curated by ChEMBL
LigandPNGBDBM50479682(2-(4-Nitrophenyl)Benzo[D]Thiazole | CHEMBL477841)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]IMPY from beta-amyloid plaques in Alzheimer's disease patient brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50479682(2-(4-Nitrophenyl)Benzo[D]Thiazole | CHEMBL477841)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asn274 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50479682(2-(4-Nitrophenyl)Benzo[D]Thiazole | CHEMBL477841)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-A...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50479682(2-(4-Nitrophenyl)Benzo[D]Thiazole | CHEMBL477841)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast cells using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2/...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
"A. Moro" University Of Bari

Curated by ChEMBL
LigandPNGBDBM50479682(2-(4-Nitrophenyl)Benzo[D]Thiazole | CHEMBL477841)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed