BDBM50482090 Annonacin::Annonacin A

SMILES [H][C@@]1(CC[C@@]([H])(O1)[C@H](O)CCCC[C@H](O)CCCCC[C@@H](O)CC1=CC(C)OC1=O)[C@H](O)CCCCCCCCCCCC

InChI Key InChIKey=XNODZYPOIPVPRF-YHLSWKNRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482090   

TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50482090(Annonacin | Annonacin A)
Affinity DataIC50:  13nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells in presence of 1% O2 by HRE3-TK-luc reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50482090(Annonacin | Annonacin A)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of chemical hypoxia-induced HIF1 activation in human T47D cells in presence of 1, 10-phenanthrolin by HRE3-TK-luc reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Homo sapiens (Human))
University Of Mississippi

Curated by ChEMBL
LigandPNGBDBM50482090(Annonacin | Annonacin A)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of chemical hypoxia-induced HIF1 activation in human T47D cells in presence of 1, 10-phenanthrolin by HRE3-TK-luc reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed