BDBM50482777 CHEBI:204928::Cefotaxime

SMILES [H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c1csc(N)n1)C(O)=O

InChI Key InChIKey=GPRBEKHLDVQUJE-QSWIMTSFSA-N

Data  19 IC50

PDB links: 7 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50482777   

TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50:  2.19E+3nMAssay Description:Binding affinity to methicillin-, vancomycin-resistant, beta-lactamase-positive Staphylococcus aureus 510 PBP2a by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: >2.81E+5nMAssay Description:Binding affinity to methicillin-, linezolid-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 2149A PBP2a by competit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50:  548nMAssay Description:Binding affinity to against methicillin-, daptomycin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 25 PBP2a by co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50: >2.81E+5nMAssay Description:Binding affinity to methicillin-resistant, heteroresistant vancomycin-intermediate, beta-lactamase-negative Staphylococcus aureus 873 PBP2a by compet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptidase(Staphylococcus aureus)
Hershey Medical Center

Curated by ChEMBL
LigandPNGBDBM50482777(CHEBI:204928 | Cefotaxime)
Affinity DataIC50:  4.39E+3nMAssay Description:Binding affinity to methicillin-resistant, vancomycin-intermediate, beta-lactamase-positive Staphylococcus aureus 1287 PBP2a by competitive binding a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed