BDBM50484296 CHEMBL1837043
SMILES FC(F)(F)c1ccc(cn1)S(=O)(=O)N1C2CC(CC1c1cn[nH]c1C2)c1ccccc1
InChI Key InChIKey=DDQNBVZKZXCOQE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50484296
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of gamma-secretase-mediated notch cleavage in human SNC-204B8 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of gamma-secretase-mediated cleavage of amyloid precursor protein in human IMR32 cells after 2 hrs using MBPC-125 substrate by ELISA assayMore data for this Ligand-Target Pair