BDBM50490612 CHEMBL2337603

SMILES [H][C@]1(CCNC1)[C@H](Oc1cccc(Cl)c1Cl)c1ccccc1

InChI Key InChIKey=MCHVXQNUHBOZIA-CXAGYDPISA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50490612   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50490612(CHEMBL2337603)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]WIN35428 from human recombinant DAT transfected in HEK293 cell membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50490612(CHEMBL2337603)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of human recombinant SERT expressed in HEK293 cells assessed as inhibition of [3H]5HT reuptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Theravance

Curated by ChEMBL
LigandPNGBDBM50490612(CHEMBL2337603)
Affinity DataIC50:  0.794nMAssay Description:Inhibition of human recombinant NET expressed in HEK293 cells assessed as inhibition of [3H]NE reuptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed