BDBM504913 6-fluoro- 1-({5-[5- (trifluoro- methyl)- 1,2,4-oxa- diazol-3- yl]pyridin- 2-yl} methyl)- 3,4-dihydro- quinolin- 2(1H)-one::US11066396, Example 317

SMILES Fc1ccc2N(Cc3ccc(cn3)-c3noc(n3)C(F)(F)F)C(=O)CCc2c1

InChI Key InChIKey=YUSKBCNMGPEOQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 504913   

TargetHistone deacetylase 6(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM504913(6-fluoro- 1-({5-[5- (trifluoro- methyl)- 1,2,4-oxa...)
Affinity DataIC50:  3.90nMAssay Description:HDAC1 and 6 reagents: FLAG-tagged HDACs 1 and 6 were prepared in-house by protein expression in HEK293F cells followed by anti-FLAG affinity purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent