BDBM50491626 CHEMBL2386155

SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc(nc1)C(F)(F)F

InChI Key InChIKey=GXYQHZGGFPEZCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491626   

TargetCytochrome P450 3A4/3A5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50491626(CHEMBL2386155)
Affinity DataIC50: >5.00E+4nMAssay Description:Reversible inhibition of CYP3A4/5 in human liver microsomes using midazolam as substrate preincubated for 30 mins followed by NADPH and substrate add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed