BDBM50492361 CHEMBL2403864
SMILES Cc1ccc2n([C@@H]3CC[C@@H](CC3)NC[C@H]3Cc4ccc(cc4C3)C#N)c(nc2c1)C(C)(C)O
InChI Key InChIKey=NULASFHNVGCWGL-NKKJXINNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50492361
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Antagonist activity at human MCHR1 expressed in CHOK1 cells assessed as inhibition of MCH/forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Hoffmann-La Roche
Curated by ChEMBL
Hoffmann-La Roche
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Displacement of [125I]MCH peptide from human MCHR1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair