BDBM50493663 CHEMBL2435008

SMILES CCOC(=O)C(=C\[C-](C(=O)c1ccc(cc1)C#N)[n+]1ccc(cc1)N(C)C)\C#N

InChI Key InChIKey=KPLSLQXSQNYXTC-QGOAFFKASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493663   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
'Al. I. Cuza' University Of Iasi

Curated by ChEMBL
LigandPNGBDBM50493663(CHEMBL2435008)
Affinity DataIC50:  4.62E+4nMAssay Description:Inhibition of recombinant human farnesyltransferase using Dansyl-GCVLS as substrate measured for 15 mins by fluorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed