BDBM50495044 CHEMBL3100124

SMILES CC1=NN(C(=O)\C1=C/c1cn(CCCCOc2cc(O)c3c(c2)oc(cc3=O)-c2ccccc2)c2ccccc12)c1cccc(Cl)c1

InChI Key InChIKey=XTMTYXNBYYKMPE-MNBJERMJSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495044   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50495044(CHEMBL3100124)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50495044(CHEMBL3100124)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by spectrophotom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed