BDBM50495462 CHEMBL3108931
SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1[C@@H](Cc2ccccc12)OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(C)(C)C
InChI Key InChIKey=YJLHAVCBMPSMFN-URPJFFLJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50495462
Affinity DataEC50: 0.400nMAssay Description:Binding affinity to cIAP1 in human MDA-MB-231 cells assessed as induction of protein degradation after 1 hr by ELISAMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University
Curated by ChEMBL
Ningxia Medical University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 0.100nMAssay Description:Induction of cIAP1 (unknown origin) degradationMore data for this Ligand-Target Pair
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Ningxia Medical University
Curated by ChEMBL
Ningxia Medical University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University
Curated by ChEMBL
Ningxia Medical University
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Binding affinity to XIAP-BIR2 domain (unknown origin)More data for this Ligand-Target Pair