BDBM50495462 CHEMBL3108931

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]1[C@@H](Cc2ccccc12)OCC#CC#CCO[C@@H]1Cc2ccccc2[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](C)NC)C(C)(C)C)C(C)(C)C

InChI Key InChIKey=YJLHAVCBMPSMFN-URPJFFLJSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50495462   

TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataEC50:  0.400nMAssay Description:Binding affinity to cIAP1 in human MDA-MB-231 cells assessed as induction of protein degradation after 1 hr by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50:  15nMAssay Description:Binding affinity to XIAP-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50:  15nMAssay Description:Binding affinity to cIAP1-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataEC50:  0.100nMAssay Description:Induction of cIAP1 (unknown origin) degradationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBaculoviral IAP repeat-containing protein 3(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50:  21nMAssay Description:Binding affinity to cIAP2-BIR3 domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP(Homo sapiens (Human))
Ningxia Medical University

Curated by ChEMBL
LigandPNGBDBM50495462(CHEMBL3108931)
Affinity DataIC50:  21nMAssay Description:Binding affinity to XIAP-BIR2 domain (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed